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Preclinical studies have demonstrated that ambroxol enhanced the antimycobacterial activity of rifampicin against intracellular BCG [27], induced autophagy through the activation of TFEB both in vitro and in vivo models, promoted mycobacterial killing in macrophages

Normally, FOXO4 prevents p53 from triggering apoptosis in aging cells, allowing them to persist and contribute to age-related diseases (1)

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doi: 10.1038/s41467-018-06603-5 97 LiuXChenSLiuLChenY

Interaction between genes and the environment The interaction between genes and the environment is crucial for understanding the complex etiology of depression