25-OHC treatment significantly inhibited sterol regulatory element-binding protein (SREBP) expression in IMS32 Xuewang cells, downregulated GXP4 and stearoyl-CoA desaturase 1 (SCD1), and upregulated PTGS2, thereby increasing intracellular ROS levels and promoting ferroptosis
Andreadis P, Karagiannis T, Malandris K, Avgerinos I, Liakos A, Manolopoulos A, et al
Avoid freezing the reconstituted solution, since freezethaw can denature the peptide
J Clin Invest 111:785793 Dvila D, Torres-Aleman I (2008) Neuronal death by oxidative stress involves activation of FOXO3 through a two-arm pathway that activates stress kinases and attenuates insulin-like growth factor I signaling
Research indicates roles in reducing acute inflammatory signaling, promoting endothelial and epithelial cell migration, and supporting tissue recovery in skeletal muscle, cardiac, and corneal models
This helps keep metabolism healthy and aids in weight management