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The gastrointestinal side effect profile was consistent with the GLP-1 agonist class: Nausea (most common, generally transient) Vomiting Diarrhea Decreased appetite Constipation These adverse events were described as generally mild and infrequently led to treatment discontinuation

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Pharmacol Rev 41:143210 Corpas FJ, Barroso JB, Carreras A, Valderrama R, Palma JM, Len AM, Sandalio LM, del Ro LA (2006) Constitutive arginine-dependent nitric oxide synthase activity in different organs of pea seedlings during plant development

doi: 10.1289/ehp.1002037 73 RodprasertWToppariJVirtanenHE

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Additional information Competing interests The authors declare that they have no competing interests