Individual response varies based on genetics, current metabolic state, and adherence to the protocol
These variations seem to affect glutathione concentrations differently
These studies demonstrate that metformin: Reduces levels of an enzyme that generates beta-amyloid proteins 32 Decreases the harmful effect of beta-amyloid on brain cell function 39-41 Reduces levels of alpha synuclein , another protein that accumulates and causes damage in Parkinsons disease 42 Prevents the loss of dopamine-producing brain cells in a model of Parkinsons disease 43,44 Improves motor coordination in a mouse model of Parkinsons 45 In 2016, a human study showed that taking 1,000 mg of metformin twice daily for 12 months improved memory recall in a group of older adults with a condition called amnestic mild cognitive impairment (a memory-stealing predecessor of Alzheimers)
This date is determined by stability studies that show how long the solution (including the benzyl alcohol) remains stable and effective
Several fatty acid beta-oxidation genes were differentially expressed with aging in the mouse olfactory bulb, including ACADM, acyl-CoA dehydrogenase family member 11 (ACAD11), hydroxyacyl-CoA dehydrogenase (HADH), hydroxyacyl-CoA dehydrogenase trifunctional protein subunit alpha (HADHA), acyl-CoA synthetase medium chain family member 3 (ACSM3), and acyl-CoA synthetase medium chain family member 4 (ACSM4) ( + ]/[NADH]
18:28 - What Are The Alternatives