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18 Patients with other autoimmune diseases, CVD, diabetes mellitus, endocrine disorders, acute and chronic pancreatic disorders, malignancy, pregnancy, breastfeeding, and those using antihyperlipidemic drugs were excluded from the study

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[83] [84] As amino acids gradually appeared in the RNA world under prebiotic conditions, [85] [86] their interactions with catalytic RNA would increase both the range and efficiency of function of catalytic RNA molecules