Initial cyber-chatter suggested that people who lose weight with GLP-1 receptor agonists also lose more fat-free mass (FFM) or lean body mass (LBM) than is desirable (though many might say that any loss of LBM or FFM is undesirable), and more than might be expected for similar weight loss achieved through caloric restriction
Influences HPA axis regulation and cortisol dynamics: The hypothalamic-pituitary-adrenal (HPA) axis governs physiological stress responses through sequential CRH, ACTH, and cortisol release
Individual studies, such as work on rat tendon and muscle healing, sit within this preclinical picture [2]
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