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This finding may explain the high prevalence of rUTI and have important therapeutic implications for chronic/recurrent bacterial infections in general

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Returning the reconstituted vial to the freezer: Freezing reconstituted peptide can cause ice crystal formation that damages the peptide

Bigini P, Larini S, Pasquali C, et al

Thats a genuinely good reason to build in breaks, and its grounded in the actual literature rather than marketing copy