Finally, pharmacological targeting of the activity of -glutamyltransferases prevents the breakdown of circulating GSH, reduces tumour cysteine levels and slows tumour growth
Because autophagy may serve as a protective mechanism for CLL cells (36), we then tested CB-839 in combination with the autophagy inhibitor chloroquine at a concentration of 50 M ( Supplemental Figure 5 )
Among them, the glutathione system made up of GSH, enzymes involved in GSH anabolism, and GSH-dependent antioxidant enzymes play a critical role in cardioprotection from oxidative stress and redox homeostasis [12,13,14]
10.1155/2015/426069 Oxid Med Cell Longev
Lean Proteins Consuming 2 to 3 servings of high-quality lean protein per day helps the body produce more glutathione
doi: 10.1128/aac.00163-19 209 KowC