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The mechanism appears to involve an increase in oxidation by means other than the degradation of NRF2

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tuberculosis also has thiol peroxidase (Tpx) and alkyl hydroperoxide peroxidase (AhpC) that respond to oxidative and nitrosative stresses imposed by macrophages

Studies have indicated that during the initial stages of thiram-induced TD, erythrocytes show diminished expression of anti-apoptotic genes, including Bcl-2, BAG-1, BAG-3 , and STAT3

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Oral administration holds particular appeal for gastrointestinal conditions