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Damage to the epithelial cells lining the stomach stops the production of intrinsic factor

The anti-aging benefits, though still largely anecdotal, have sparked curiosity, with some claiming clearer skin and improved muscle tone

By inhibiting this interaction, FOXO4-DRI allows reactivation of the apoptotic pathway in non-proliferative senescent cells, leading to their selective elimination without damaging healthy tissue

But it does need to combine with intrinsic factor, a protein made by your stomach, to be absorbed into your body

Some people report less pain and easier movement within a month, while for others the benefit takes longer to become clear