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A small study of 10 healthy volunteers revealed significant decreases in lipid oxidation products (-33%) and total cholesterol (-12%), with a concomitant increase in HDL cholesterol (29%) when using 500 mg curcumin daily for seven days

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579 In addition, metabolic disorders of neuronal Ca 2+ can drive ferroptosis through interactions with iron and crosstalk between the ER and mitochondria, and maintaining Ca 2+ homeostasis to inhibit ferroptosis may be an innovative target for the treatment of AD

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Drug Metab Dispos 19(5):900906 Elzagallaai AA, Sultan EA, Bend JR, Abuzgaia AM, Loubani E, Rieder MJ (2020) Role of oxidative stress in hypersensitivity reactions to sulfonamides