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Studied for anti-inflammatory effects in gastrointestinal research models, with NF-kB pathway modulation as the principal proposed mechanism

Tram NK, McLean RM, Swindle-Reilly KE

They are linked through overlapping pathways including NF-B activation, elevated TNF-, and IL-6 that drive both gut permeability and systemic insulin resistance.13 Peptide therapies for insulin resistance increasingly recognize this connection

doi: 10.1002/ddr.10110

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Our model also provides crucial insights for the design or optimization of artificial glutaredoxins, transition-state inhibitors and glutaredoxin-coupled redox sensors