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PMC 416462

It was developed by Russian researchers as part of a systematic effort to create low-molecular-weight neurotrophin mimetics

Ultimately, as a monotherapy, DRP-104 demonstrates notable anti-tumor activity, with further enhanced therapeutic efficacy when used in combination with checkpoint blockade therapy, leading to improved survival and long-term durable cures [186]

doi: 10.4103/NRR.NRR-D-24-01019 4

Ma LL, Wang YY, Yang ZH, Huang D, Weng H, Zeng XT (2020) Methodological quality (risk of bias) assessment tools for primary and secondary medical studies: what are they and which is better