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One way that mycotoxins, such as aflatoxin, are removed from the body is by conjugation with glutathione.[ref] Related article: Mycotoxins and genetic variants related to detoxification Acetaminophen: The metabolism of acetaminophen produces a toxic metabolite called NAPQI, which is neutralized and excreted by conjugation with glutathione

and inhibition of caspase-3-mediated degradation of FOXO3a (52)

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Overall, these data strongly support that lapatinib exerts an inhibitory role on neuronal ferroptosis by blocking the downregulation of GPX4

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