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2).42 The polymorphism in uridine diphosphoglucuronosyl transferase enzymes (UGTs) activity is also identified between human populations.47 Hence, another proposed mechanism for hepatotoxicity induced by antithyroid agents could be attributed to their impaired detoxification process, due to lower activity of UGTs

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Also, patients should be warned about the danger of taking folic acid in place of vitamin B 12, because the former may prevent anemia but allow progression of subacute combined degeneration