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SOD is the primary 2 scavenger and the first defensive component against ROS [41]

Chemphyschem 12 , 397404 (2010)

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The inhibition of PI3K/Akt and ERK1/2 also significantly decreased NAMPT-induced VEGF expression and activation, leading to important inhibition of endothelial cell proliferation and in the formation of new vessels

doi: 10.1186/s10020-021-00368-2 178 ZhangYHanSKongMTuQZhangLMaX