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The Center for Drug Evaluation and Research (CDER) warning letters jumped 50% in fiscal year 2025

Academic Press, Cambridge, MA, USA (2019)

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The antioxidant Dl-3-n-butylphthalide can hinder the NLRP3 inflammasome and decrease the severity of AD-like symptoms by affecting the Nrf2-TXNIP-TrX pathway (Wang et al., 2019)