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Peer review Peer review information Nature Medicine thanks Frederic Sitas and the other, anonymous, reviewer(s) for their contribution to the peer review of this work

"Don't flick that cigarette over here!" Our hint: A three word answer

The overall rate was still falling, but as health officials and governments learned more and more about just how deadly smoking was, policy responses followed

This equates to nearly seven hours of life lost when smoking an average pack of 20 cigarettes

Kashyap's producer friends and acquaintances advised him to have a major actor back the idea