Participants will undergo a urinary cotinine test (to detect any nicotine use), an exhaled CO test, and complete self-administered questionnaires (DASS 21, FTND, AUDIT, SF-36, QSU-brief, PHQ-9, MNWS, mCEQ, and concomitant medication record)
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The GABA-ergic and glutamatergic effects of alcohol are region-specific and sex-selective, which are influenced by sex differences in the composition of the respective receptor subunits 41
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Significant increases in genotoxicity or expression of proteins involved in mutagenesis were found following acute exposure to nicotine e-cigarette in 6 studies 28,34-37,42 , following short-to-medium term exposure in 1 study 33 , and following non-nicotine e-cigarette exposure in 1 study 25
