Gastroenterology 125, 654659
Lindahl, V
In overweight/obese PCOS women with vitamin D deficiency, daily administration of 1,000 mg of calcium combined with 50,000 IU of vitamin D weekly for 8 weeks revealed that calcium supplementation, with or without additional vitamin D, resulted in significant diminutions in FBG, FINS, HOMA-IR, TG, and VLDL-C, along with a notable increase in the QUICKI (117)
This functional deficiency is most commonly seen in patients with liver or kidney disease
Oliveira-Ferreira et al., 2019), and apoptosis as typical cellular death (Rossi et al., 2007
however, evidence is emerging that increased cellular GSSG accumulation may be of equal, if not greater, importance in regulating oxidative stress-triggered detrimental effects