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then, at the level of the genome, it binds to the specific transcription factors to trigger the expression of specific genes [90]

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Results: Participants (60% male, 60% neurology specialists/trainees, 60% 5-10 years of clinical experience) identified the key decision-making issues of clinical indicators, clinician experience, access to resources, and involvement of the patient and family

Consequently, the cytosolic probe for confocal imaging was changed to coumarin chloroalkane (Comcl), which fluoresces in a distinct spectral window, thereby enabling clear spatial separation of cytosolic and periplasmic signals

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Stampfer et al, 1992)