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Food and Drug Administration (FDA) : Not approved as a drug or dietary supplement

The paucity of well-controlled clinical studies complicates the confirmation of whether the mechanisms identified in animals are directly applicable to humans

It is caused by repeated amplification of the CAG trinucleotide in the huntingtin (Htt) gene on the short arm of chromosome 4, which leads to a prolonged polyglutamine stretch at the N-terminus of the protein

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(2005) [92] revealed the presence of the carnitine transporter OCTN2 in Sertoli cells and whole-testis tissue samples evaluated by RT-PCR and Western blotting analysis

10.1017/s0080456800031203 77 BroccaS.TestaL.SobottF.amalikovaM.NatalelloA.PapaleoE.et al (2011)