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We proposed that HSCs could sense aging-associated intrinsic or extrinsic cellular insults and initiate epigenetic inflammatory training, resulting in heightened inflammatory response to aging-associated damage-associated molecular patterns in distant tissues

Mocchegiani E, Giacconi R, Cipriano C, Malavolta M

van Smaalen, T

Assessing causality in epidemiology: revisiting Bradford Hill to incorporate developments in causal thinking

One of the most significant issues is their high inter-donor variability, which significantly impairs data reproducibility and limits further bioinformatic data analysis

Cuccaro R, Masini M, Malanho Silva J, Camponeschi F, Banci L