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The recommended starting dosages of benzbromarone range from 12.5 mg to 50 mg daily, a regimen predominantly observed in Europe and Asia

The terminal half-life was determined based on the terminal slope, which was obtained by converting the micro-constants from the 2-compartment model to macro constants ( 03hr ) was obtained by integrating the curve over this time period, while the total AUC (AUC 0- ) was derived using the dose divided by clearance

ROS as signalling molecules: mechanisms that generate specificity in ROS homeostasis

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