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LL-37 possesses immunomodulatory properties that influence various immune cells, including neutrophils, macrophages, dendritic cells, and lymphocytes (Nagaoka et al., 2001)

Neuroendocrinology , 2022 , 112

all these biomolecules play important synergistic role as a defense mechanism from free radicals thereby protecting living cells/organs from oxidative damage

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The M2 macrophages are characterized as an anti-inflammatory phenotype, demonstrating high Arg-1 expression and producing anti-inflammatory effects (73, 74)

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