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Loren Pickart estimated the lethal dose at approximately 22,500 mg for humans, which is 300-fold above effective doses

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Micropuncture cholecystectomy versus conventional laparoscopic cholecystectomy: a randomized controlled trial

We identify a previously unrecognized metabolic reprogramming of ILC2s induced by melatonin, characterized by diversion of glucose and mitochondrial metabolism toward glutathione synthesis

10.1093/nar/gkr1191