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Analytische kwaliteit Voor deze verbinding is de identiteit en zuiverheid van het uitgangsmateriaal bepalend voor de interpreteerbaarheid van analytische resultaten

155 Additionally, targeting bile acid metabolism, such as through bile acid sequestrants and farnesoid X receptor agonists, has shown promise in preclinical models by reducing bile acid accumulation and hepatotoxicity

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Finally, the absence of validated biomarkers for predicting treatment response or monitoring efficacy further complicates both clinical research and practical application, limiting the ability to personalize therapy or objectively assess outcomes