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Some practitioners in the peptide community do recommend stacking AOD 9604 with GLP-1 agonists, particularly for patients who want to maximize fat loss while minimizing muscle loss

( McGuff Medical

Savannah Medical Weight Loss Programs Struggling with weight loss despite diet and exercise

This means B12 deficiency is real and underdiagnosed, but it is not universal and not everyone experiencing fatigue has a B12 problem

So, for those still struggling with weight despite the influx of new treatment options, have no fear

But in practice, these two compounds produce completely different outcomes, work through fundamentally different mechanisms, and carry very different risk profiles