Some benefit from weekly shots, others less often
These peripheral and central deficits can include severe gastrointestinal lesions, intracranial (superior sagittal sinus) hypertension, brain swelling and lesions, portal and caval hypertension, aortic hypotension, peripheral and central thrombosis, inferior caval vein and superior mesenteric vein congestion, azygos vein failure, electrocardiogram (ECG) disturbances, and heart, lung, liver, and kidney lesions (Vukojevic et al., 2018
Add the fact that BPC-157's patent expires in 2033, and the math is clear: no pharmaceutical company was ever going to drop $500M on Phase III trials for a molecule they couldn't monopolize
Future research applications will likely expand to include investigation of senescence heterogeneity, tissue-specific senescent cell populations, and the development of personalized approaches to senolytic intervention based on individual senescent cell burden and characteristics
They act on blood sugar, inflammation, and hormone balance
The titration schedule is a maximum framework, not a mandatory escalation
