Inflammopharmacology 25(2):255264 Drmic D, Kolenc D, Ilic S, Bauk L, Sever M, Zenko Sever A et al (2017) Celecoxib-induced gastrointestinal, liver and brain lesions in rats, counteraction by BPC 157 or L-arginine, aggravation by L-NAME
The diagnosis of 5-oxoprolinase deficiency is established by: Low activity of 5-oxoprolinase in nucleated cells such as leukocytes or cultured skin fibroblasts (5-oxoprolinase is not present in erythrocytes)
Ive personally used BPC-157 for everything from torn rotator cuffs to gut inflammation, and Ive watched it work near-miracles in recovery scenarios where conventional medicine offered nothing but NSAIDs and wait it out. But nowhere in its primary mechanisms of action will you find direct interaction with Leydig cells in the testes, luteinizing hormone (LH) signaling, or the hypothalamic-pituitary-gonadal (HPG) axis
Yuen MF, Asselah T, Jacobson IM, Brunetto MR, Janssen HLA, Takehara T, Hou JL, Kakuda TN, Lambrecht T, Beumont M, Kalmeijer R, Guinard-Azadian C, Mayer C, Jezorwski J, Verbinnen T, Lenz O, Shukla U, Biermer M, REEF-1 Study Group
They can also help determine the best dosage and form for your needs
R.FranklinB
