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If you have an iodine deficiency, though, you will absorb more

Headaches: NAD+ supplements can cause headaches, particularly if you are sensitive to nicotinic acid (the component of NAD+ that gives niacin its name)

PMID: 36331676

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Gastrointest Endosc 2005;61:28-31

Because of the toxicity of cysteine, and possibly even of methionine supplements given in excess, and the intrinsic problems associated with an induced amino acid imbalance, proteins rich in SAA have been considered as supplements