labial melanotic Macules: Dark Spots on the Lip Mystery behind labial and oral

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Plos ONE 7 , e52570 (2012)

For Arbutin_c, it stably interacts with four key residues: D180, E184, S165, and S361 (Table 2)

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Many times, creams and serums work only on the surface, while the real issue lies deepercaused by factors like pollution, stress, poor diet, and sun exposure