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Following neutralization with (NH) 4 HCO 3 , samples were frozen at 20 C for 20 min, spun and supernatants measured directly

Ingredients are 1/2 small beetroot (peeled and chopped), 1/2 banana (for creaminess and natural sweetness), 1/2 cup coconut water or almond milk (for hydration), 1/4 cup Greek yogurt (for protein and smooth texture) and 1/2 teaspoon honey (optional, for added sweetness)

This mechanism means AOD-9604 does not require appetite suppression to be effective, making it suitable for individuals who do not struggle with appetite control or who cannot tolerate the gastrointestinal side effects common with GLP-1 agonists