Due to the large absorptive area and a rich vascular supply, the orobuccal mucosa allows a rapid absorption of glutathione and other substances by passive transport through or around the cells into the abundant capillary circulation
Heinemann U
Acknowledgements We are grateful to the stroke patients for their participation in the research and to the staff from the ISTBI, Huashan Hospital, and National Clinical Research Center for Geriatric Diseases in the clinic study
Glutathione is made up of amino acids (glutamine, glycine and cysteine) and has amazing health benefits (glutathione article)
Despite that mitochondria are exposed to the generation of oxidant species, the existence of an efficient antioxidant defense system, of which mGSH is a critical component, prevents or repairs oxidative damage generated during normal aerobic metabolism ( MITOCHONDRIAL ROS GENERATION AND DEFENSE Reactive oxygen species can be generated in several intracellular sites, including cytosol, peroxisomes, plasma membrane, and ER
Bu toksik maddelerden bazlar unlardr: Asetaminofen (parasetamol), aseton, zcler, ar metaller (civa, di dolgular, alar, dvmeler, kurun kadmiyum vb) akaryakt ve yan rnleri, yapay tatlandrc aspartam, ev temizlik rnleri (deterjanlar, yumuatclar, oda kokular vb), sentetik gda boyalar, mutfak malzemeleri (teflon tavalar, plastik saklama kaplar, karton ambalajlarn i kaplamalar vb), klorlu su, UV radyasyon, elektromanyetik alanlar, alkol, sigara duman, mangal duman, fotokopi ve printer toner mrekkepleri, endstriyel atklar -Dier d faktr olarak yetersiz beslenme de glutatyon sentezinde gerekli kofaktrler olan vitamin ve minerallerin eksiklii sonucunda glutatyon sentezi yetersiz kalr, baka antioksidanlarn yetersizlii de glutatyonun ar harcanmasna neden olur
