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Comparison Both work on fat metabolism

Dialing down NNMT activity theoretically raises NAD+ precursor availability and pushes fat cells toward burning energy rather than storing it

References Journal of Endocrinology and Metabolism (2014) Safety and metabolism of AOD9604 as a nutraceutical ingredient

There are specific scenarios where combining these two forms of B12 might be considered, as part of a tailored treatment plan: Reducing Injection Frequency: For some individuals who require lifelong B12 due to malabsorption but dislike frequent injections, a doctor might explore if high-dose oral supplements can help maintain adequate levels between less frequent injections

In doing so, you will have guaranteed the lifespan of your vials

Therefore, sourcing wellness compounds from reputable suppliers remains important