The FOXO4-DRI peptide has been studied in laboratory settings exploring its interaction with intracellular regulatory proteins and signalling complexes associated with senescent cellular states
Identification of renox, an NAD(P)H oxidase in kidney
Article References Running Head: Oxidants and Antioxidants Funding Support: This study was supported by the National Science Center, Poland (grant 2015/17/B/NZ5/01370)
Definitive negative trial: A subsequent well-designed 2-year study among 85 adults (average age 59) with progressive MS showed that taking 1,200 mg of alpha-lipoic acid with food once daily did not improve mobility, cognition, or quality of life, and did not reduce the frequency of falls, overall disability, fatigue, or pain compared to placebo
Now, this is where it gets interesting for researchers
RavelJGajerPAbdoZSchneiderGMKoenigSSMcCulleSLet al