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A deficiency in glutathione can lead to increased oxidative stress, reduced detoxification capacity, and compromised liver function

2010;2:26ra26

Therapeutic strategies targeting selective autophagy, such as AMPK activators and natural compounds, have shown promise in restoring mitochondrial homeostasis and alleviating cognitive deficits in diabetic animal models

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Consistent with the findings in IRI model, GSH levels were reduced in the kidney of sulfasalazine-treated mice (Supplemental Figure 9F), presumably reflecting the attenuation of the formation of TLS