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[DOI] [PubMed] [Google Scholar] 22.Skelton IV WP, Skelton M, Vesely DL

The position of the R-domain informs on the phosphorylation-dependent activation mechanism and provides clarification on the competing models that exist

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Clinical studies have shown that patients with the stromal subtype generally present with more advanced disease at diagnosis and have a poorer prognosis, whereas patients with the immunoreactive subtype may be diagnosed at earlier stages and tend to respond more favorably to standard treatments ( Furthermore, the tumor microenvironment (TME) of HGSOC displays distinct characteristics across various subtypes