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54 Meta-analyses of clinical trials of bupropion show that its impact on long-term abstinence is similar to NRTs (e.g., yielding abstinence in about 25% of users, an increase in abstinence of about 50% to nearly 80% relative to placebo) 17 , 104 , 122 , 123 (Table 3.2)

10.3390/ph16111542 16 BenowitzN

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Acknowledgments The research was supported by the Lotte & John Hecht Memorial Foundation, Grant Number 3693 ( with core support from the BC Cancer Foundation and the BC Cancer Agency, to GK