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It is a narcotic, and can lead to Narcotic Addiction with use

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tobacco companies sued the federal government Tuesday over new graphic cigarette labels that include the sewn-up corpse of a smoker and a picture of diseased lungs, saying the warnings violate their free speech rights and will cost millions of dollars to print

This can lead to ROS production and the release of damage-associated molecular patterns (DAMPs), which are pro-inflammatory molecules (32)

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