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When demand risesthrough inflammation, toxin exposure, or intense physiologic stresscells can burn through antioxidant capacity faster than it is restored

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Figure 6 Figure 7 3.3 NLRs and inflammasomes NLRs play crucial roles not only in sensing PAMPs and DAMPs but also in detecting disturbances in cellular homeostasis, such as redox imbalance, ion flux, and other forms of cellular stress (57)

These findings suggest that AS-IV holds considerable potential for mitigating DOX-induced cardiotoxicity

There are various mechanisms for drug molecules to cross the BBB