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The main function of NLRP3 inflammasome is an activation of caspase-1, maturation of IL-1 and IL-18 (He et al

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Resolvin E1 improves the maturation of porcine oocytes by suppressing oxidative stress via Nrf2 pathway activation

Professor Muresanus research contributions include: Principal investigator for the CARS trial (Cerebrolysin and Recovery After Stroke), the largest randomized controlled trial examining functional outcomes Lead investigator for CAPTAIN trials evaluating Cerebrolysin in traumatic brain injury populations Extensive research on neurotrophic factor signaling and neuroprotective mechanisms Development of multimodal therapeutic strategies combining Cerebrolysin with rehabilitation Investigations of dose-response relationships and optimal treatment protocols across neurological conditions His work has been instrumental in advancing understanding of peptidergic neuroprotection, though clinical translation challenges remain a focus of ongoing investigation

Soong, Jonathan