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37 Necroptosis is a regulated form of necrotic cell death initiated by the binding of tumor necrosis factor (TNF)- to its receptor TNFR1, forming a multiprotein signaling complex

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While preclinical models have yielded valuable insights into microglial heterogeneity, many markers defined in rodent systems [e.g., arginase 1 (Arg1) or rodent-specific chitinase-like protein (Ym1)] have limited expression or different regulation in human microglia

10.1039/b707313e 37 HiguchiE