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Catalpol protects against spinal cord injury in mice through regulating MicroRNA-142-Mediated HMGB1/TLR4/NF-B signaling pathway
It's like comparing apples to orangeseach has its own unique benefits
It counteracts the increases of pro-inflammatory and pro-cachectic cytokines, such as IL-6 and TNF-, and the expression of FoxO3a, p-AKT, and P-GSK-3
doi: 10.1016/j.arr.2016.10.005 114 FontanaLVillarealDTDasSKSmithSRMeydaniSNPittasAGet al
To put that in perspective, you'd need massive amounts of oral supplements to come close to these therapeutic doses - and most wouldn't make it to your cells intact