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This broad applicability makes it particularly interesting for complex ankle injuries that often involve damage to multiple structures

The standard treatment ladder goes something like this: start with joint supplements (glucosamine, chondroitin), add omega-3 fatty acids, move to NSAIDs when things get bad, then consider surgery or prescription pain management

[8] Serious adverse effects are uncommon

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We typically recommend weekly injections for the first month, and then monthly maintenance injections after that

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