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Regular treatment and follow-up care can help ensure that vitamin B12 levels remain within a healthy range

[DOI] [PubMed] [Google Scholar] 101.Jandric I., Vrcic H., Jandric Balen M., Kolenc D., Brcic L., Radic B., Drmic D., Seiwerth S., Sikiric P

In the UK, standard maintenance therapy for pernicious anaemia is typically hydroxocobalamin 1mg by intramuscular injection every three months (or every two months if neurological symptoms are present), as per BNF and NICE guidance

Important caveat: the combination is not clinically validated

Microdosing starts at doses below the lowest commercially available starting dose and is titrated slowly to achieve neuromodulatory and metabolic effects without the full appetite suppression or side effects of standard dosing