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This can cause estrogen levels to build up

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Effect of N-acetylcysteine on the pulmonary response to endotoxin in the awake sheep and upon in vitro granulocyte function

Neuraminidase alters red blood cells in sepsis

Advanced glycation end-products (AGEs) create abnormal cross-links that stiffen collagen fibers, reducing their ability to support smooth skin and increasing brittleness that leads to deeper wrinkle formation

Havent done it in people yet. Sikirics recent review does reference some human studies