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Calcitriol/VDR signaling can activate pro-apoptotic proteins and suppress anti-apoptotic ones

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Moreover, omega-3 PUFAs can enhance a cells endogenous antioxidant capabilities through multiple mechanisms: they can increase the activity of enzymes involved in antioxidant defense, such as glutathione peroxidase and superoxide dismutase, thus enhancing resistance to ROS-induced damage and reducing lipid peroxidation