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An experimental study showed that Beclin-1 and LC3 levels were increased, whereas Bcl-2 level was reduced within 48 h following seizure in rats (Li et al

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This interaction with SIRT1, a key enzyme in cellular stress response and longevity, opens new research directions

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A separate meta-analysis that pooled results of trials in older adults with mild cognitive impairment found B-vitamin supplementation (6 to 24 months, depending on the trial) had no benefits on various cognitive parameters, including executive function, information processing speed, and episodic memory (90)