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A source from the science community commented, "It's true the corresponding author should have overseen the paper before publication, but realistically, it's difficult to catch manipulation if the first author is determined to do it, as it would require re-running experiments and re-examining every piece of data." They also pointed out, "Reviewers are also busy writing their own papers, and it's hard to be diligent in an unpaid reviewer role with no compensation." The responsibility for these processes is left to individuals, and there is no support system in place

Notably, lactate-derived lactylation correlates with higher S-AKI incidence and poor prognosis in clinical sepsis patients

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Free Radic Biol Med 2015

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These studies indicate that ALOX12 is necessary for p53-mediated ferroptosis [74]